Structure of PDB 5yk4 Chain B

Receptor sequence
>5yk4B (length=767) Species: 242231 (Neisseria gonorrhoeae FA 1090) [Search protein sequence]
SAVSPMMQQYLGIKAQHTDKLVFYRMGDFYELFLDDAVEAAKLLDITLTT
RGQMDGVPIKMAGVPFHAAEQYLARLVKLGKSVAICEQVGEVGAGKGPVE
RKVVRIVTPGTLTDSALLEDKETNRIVAVSPDKKYIGLAWASLQSGEFKT
KLTTADKLNDELARLQAAEILLPDSKNAPQLQTASGVTRLNAWQFAADAG
EKLLTEYFGCQDLRGFGLDSKEHAVSIGAAGALLNYIRLTQNLMPQHLDG
LSLETDSQYIGMDAATRRNLEITQTLSGKKTPTLFSILDGCATHMGSRLL
ALWLHHPLRNRAHIRARQEAVTALESQYEPLQCHLKSIADIERIAARIAV
GNARPRDLASLRDSLFELAQIDLSATGSSLLETLKAVFPETLPVAETLKA
AVMPEPSVWLKDGNVINHGFHPELDELRRIQNHGDEFLLDLEAKERERTG
LSTLKVEFNRVHGFYIELSKTQAEQAPADYQRRQTLKNAERFITPELKAF
EDKVLTAQDQALALEKQLFDGVLKNLRTALPQLQKAAKAAAALDVLSTFS
ALAKERNFVRPEFADYPVVHIENGRHPVVEQQVRHFTANHTDLDHKHRLM
LLTGPNMGGKSTYMRQVALIVLLAHTGCFVPADAATIGPVDQIFTRVEMS
ETAYILHHATEQSIVLMDEVGRGTSTFDGLALAHAIAEHLLQKNKSFSLF
ATHYFELTYLPEAHAAAVNMHLSALEQGRDIVFLHQIQPGPAGKSYGIAV
AKLAGLPVRALKAAQKH
3D structure
PDB5yk4 Mechanism of formation of a toroid around DNA by the mismatch sensor protein.
ChainB
Resolution2.97 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ADP B F589 T590 N609 G612 K613 S614 T615 H753 F586 T587 N606 G609 K610 S611 T612 H735
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003684 damaged DNA binding
GO:0005524 ATP binding
GO:0030983 mismatched DNA binding
GO:0140664 ATP-dependent DNA damage sensor activity
Biological Process
GO:0006281 DNA repair
GO:0006298 mismatch repair
Cellular Component
GO:0005829 cytosol

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5yk4, PDBe:5yk4, PDBj:5yk4
PDBsum5yk4
PubMed29182773
UniProtQ5F5J4|MUTS_NEIG1 DNA mismatch repair protein MutS (Gene Name=mutS)

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