Structure of PDB 5yi2 Chain B

Receptor sequence
>5yi2B (length=145) Species: 272623 (Lactococcus lactis subsp. lactis Il1403) [Search protein sequence]
MSLANQIDQFLGTIMQFAENKHEILLGKCESDVKLTSTQEHILMLLAEQI
STNAKIAEKLKISPAAVTKALKKLQEQELIKSSRATNDERVVLWSLTEKA
VPVAKEHATHHEKTLSTYQELGNKFTDEEQEVISKFLSALTEEFQ
3D structure
PDB5yi2 Allosteric histidine switch for regulation of intracellular zinc(II) fluctuation.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B N54 A55 P65 A66 T69 N53 A54 P64 A65 T68 PDBbind-CN: Kd=72nM
BS02 dna B T37 T39 I63 S64 A67 K70 T36 T38 I62 S63 A66 K69 PDBbind-CN: Kd=72nM
BS03 ZN B E24 H42 H108 H112 E23 H41 H107 H111
BS04 ZN B C30 E41 E107 C29 E40 E106
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003700 DNA-binding transcription factor activity
GO:0008270 zinc ion binding
GO:0046872 metal ion binding
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function

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Biological Process
External links
PDB RCSB:5yi2, PDBe:5yi2, PDBj:5yi2
PDBsum5yi2
PubMed29229866
UniProtQ9CDU5

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