Structure of PDB 5ydr Chain B

Receptor sequence
>5ydrB (length=250) Species: 9606 (Homo sapiens) [Search protein sequence]
MPKCIQCGQYLDDPDLKYGQHPPDAVDEPQMLTNEKLSIFDANESGFESY
EALPQHKLTCFSVYCKHGHLCPIDTGLIEKNIELFFSGSAKPIYDDDPSL
EGGVNGKNLGPINEWWITGFDGGEKALIGFSTSFAEYILMDPSPEYAPIF
GLMQEKIYISKIVVEFLQSNSDSTYEDLINKIETTVPPSGLNLNRFTEDS
LLRHAQFVVEQVESYDEAGDSDEQPIFLTPCMRDLIKLAGVTLGQRRAQA
3D structure
PDB5ydr Structural and mechanistic insights into UHRF1-mediated DNMT1 activation in the maintenance DNA methylation.
ChainB
Resolution2.003 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.1.1.37: DNA (cytosine-5-)-methyltransferase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN B C353 C356 C414 H418 C4 C7 C65 H69
External links
PDB RCSB:5ydr, PDBe:5ydr, PDBj:5ydr
PDBsum5ydr
PubMed29471350
UniProtP26358|DNMT1_HUMAN DNA (cytosine-5)-methyltransferase 1 (Gene Name=DNMT1)

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