Structure of PDB 5ya2 Chain B

Receptor sequence
>5ya2B (length=478) Species: 83333 (Escherichia coli K-12) [Search protein sequence]
SKYYLMALDAGTGSIRAVIFDLEGNQIAVGQAEWRHMEFDLNKNWQLACE
CMRQALHNAGIAPEYIAAVSACSMREGIVLYNNEGAPIWACANVDARAAR
EVSELKELHNNTFENEVYRATGQTLALSAIPRLLWLAHHRSDIYRQASTI
TMISDWLAYMLSGELAVDPSNAGTTGLLDLTTRDWKPALLDMAGLRADIL
SPVKETGTLLGVVSSQAAELCGLKAGTPVVVGGGDVQLGCLGLGVVRPAQ
TAVLGGTFWQQVVNLAAPVTDPEMNVRVNPHVIPGMVQAESISFFTGLTM
RWFRDAFCAEEKLIAERLGIDTYTLLEEMASRVPPGSWGVMPIFSDHAAP
SFINLSIDPDKCNKATLFRALEENAAIVSACNLQQIADFSNIHPSSLVFA
GGGSKGKLWSQILADVSGLPVNIPVVKEATALGCAIAAGVGAGIFSSMAE
TGERLVRWERTHTPDPEKHELYQDSRDK
3D structure
PDB5ya2 Evidence of link between quorum sensing and sugar metabolism inEscherichia colirevealed via cocrystal structures of LsrK and HPr
ChainB
Resolution2.701 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.189: autoinducer-2 kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ADP B G315 R319 R322 Y341 G428 G432 G297 R301 R304 Y323 G402 G406
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0016301 kinase activity
GO:0071518 autoinducer-2 kinase activity
Biological Process
GO:0005975 carbohydrate metabolic process
GO:0009372 quorum sensing
GO:0016310 phosphorylation
GO:0044010 single-species biofilm formation
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ya2, PDBe:5ya2, PDBj:5ya2
PDBsum5ya2
PubMed29868643
UniProtP77432|LSRK_ECOLI Autoinducer-2 kinase (Gene Name=lsrK)

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