Structure of PDB 5y9d Chain B

Receptor sequence
>5y9dB (length=682) Species: 284591 (Yarrowia lipolytica CLIB122) [Search protein sequence]
TTNTFTDPPVEMAKERGKTQFTVRDVTNFLNGGEEETQIVEKIMSSIERD
PVLSVTADYDCNLQQARKQTMERVAALSPYLVTDTEKLSLWRAQLHGMVD
MSTRTRLSIHNNLFIGSIRGSGTPEQFKYWVKKGAVAVKQFYGCFAMTEL
GHGSNLKGLETTATYDQDSDQFIINTPHIGATKWWIGGAAHTSTHCVCFA
KLIVHGKDYGTRNFVVPLRNVHDHSLKVGVSIGDIGKKMGRDGVDNGWIQ
FTNVRIPRQNMLMRYAKVSDTGVVTKPYGALIRGRVSMIADSFHVSKRFL
TIALRYACVRRQFGTSGDTKETKIIDYPYHQRRLLPLLAYCYAMKMGADE
AQKTWIETTDRILALNPNDPAQKNDLEKAVTDTKELFAASAGMKAFTTWG
CAKIIDECRQACGGHGYSGYNGFGQGYADWVVQCTWEGDNNVLCLSMGRG
LVQSALQILAGKHVGASIQYVGDKSKISQNGQGTPREQLLSPEFLVEAFR
TASRNNILRTTDKYQELVKTLNPDQAFEELSQQRFQCARIHTRQHLISSF
YARIATAKDDIKPHLLKLANLFALWSIEEDTGIFLRENILTPGDIDLINS
LVDELCVAVRDQVIGLTDAFGLSDFFINAPIGSYDGNVYEKYFAKVNQQN
PATNPRPPYYESTLKPFLFREEEDDEICDLDE
3D structure
PDB5y9d Structural insight into the substrate specificity of acyl-CoA oxidase1 from Yarrowia lipolytica for short-chain dicarboxylyl-CoAs.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 1.3.3.6: acyl-CoA oxidase.
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 FAD B R317 Y334 R340 A418 G421 Y424 R310 Y327 R333 A411 G414 Y417
BS02 FAD B M148 T149 G154 S155 W186 I187 V439 W443 D446 V449 M147 T148 G153 S154 W185 I186 V432 W436 D439 V442
Gene Ontology
Molecular Function
GO:0003997 acyl-CoA oxidase activity
GO:0005504 fatty acid binding
GO:0016491 oxidoreductase activity
GO:0016627 oxidoreductase activity, acting on the CH-CH group of donors
GO:0050660 flavin adenine dinucleotide binding
GO:0071949 FAD binding
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006635 fatty acid beta-oxidation
GO:0033540 fatty acid beta-oxidation using acyl-CoA oxidase
GO:0055088 lipid homeostasis
Cellular Component
GO:0005777 peroxisome

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:5y9d, PDBe:5y9d, PDBj:5y9d
PDBsum5y9d
PubMed29198706
UniProtO74934|ACOX1_YARLI Acyl-coenzyme A oxidase 1 (Gene Name=POX1)

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