Structure of PDB 5y41 Chain B

Receptor sequence
>5y41B (length=232) Species: 9606 (Homo sapiens) [Search protein sequence]
PPVSLISALVRAHVDSNPAMTSLDYSRFQANPDTQHIQQFYDLLTGSMEI
IRGWAEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCN
GVVLHRLQCVRGFGEWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERH
GLKEPKRVEELQNKIVNCLKDHVTFNNGGLNRPNYLSKLLGKLPELRTLC
TQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
3D structure
PDB5y41 PGE1 and PGA1 bind to Nurr1 and activate its transcriptional function.
ChainB
Resolution2.05 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 RPG B E440 S441 F443 L444 R515 C566 L591 T595 P597 E74 S75 F77 L78 R149 C200 L225 T229 P231
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5y41, PDBe:5y41, PDBj:5y41
PDBsum5y41
PubMed32451509
UniProtP43354|NR4A2_HUMAN Nuclear receptor subfamily 4 group A member 2 (Gene Name=NR4A2)

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