Structure of PDB 5xwa Chain B

Receptor sequence
>5xwaB (length=98) Species: 9823 (Sus scrofa) [Search protein sequence]
SSGSSYPSLLQCLKAPVLSDSSCKSSYPGQITGNMICVGFLEGGKDSCQG
DSGGPVVCNGQLQGIVSWGYGCAQKNKPGVYTKVCNYVNWIQQTIAAN
3D structure
PDB5xwa Tripeptides derived from reactive centre loop of potato type II protease inhibitors preferentially inhibit midgut proteases of Helicoverpa armigera.
ChainB
Resolution1.9 Å
3D
structure
Catalytic site residues are labeled in the structure
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Enzymatic activity
Catalytic site (original residue number in PDB) Q182 G183 D184 S185 G186
Catalytic site (residue number reindexed from 1) Q49 G50 D51 S52 G53
Enzyme Commision number 3.4.21.4: trypsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B D179 S180 C181 Q182 G183 S185 S200 W201 G202 D46 S47 C48 Q49 G50 S52 S67 W68 G69
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:5xwa, PDBe:5xwa, PDBj:5xwa
PDBsum5xwa
PubMed29486250
UniProtP00761|TRYP_PIG Trypsin

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