Structure of PDB 5xux Chain B

Receptor sequence
>5xuxB (length=224) Species: 192952 (Methanosarcina mazei Go1) [Search protein sequence]
MDRPFIFINSAMSADGKLSTKERKQVKISGKLDFERMDELRAHADAIMVG
IGTVLADDPSLTVKSPERKAARKAAGKSENPVRVVVDSSARTPLNADIFK
KGEGLRIIAVSNSAPEEKIRMLEEKALVIKTGAFRVDLTELAAKLKEMGI
NSLMVEGGATLNWGMLSAGLVDEVYTFVGNLIIGGKTAPTFTDGEGFTEN
ELLGLELSSAEKIEDGILLKWKVK
3D structure
PDB5xux Evolution of archaeal Rib7 and eubacterial RibG reductases in riboflavin biosynthesis: Substrate specificity and cofactor preference.
ChainB
Resolution2.27 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 1.1.1.302: 2,5-diamino-6-(ribosylamino)-4(3H)-pyrimidinone 5'-phosphate reductase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 NAP B S10 A11 L18 S19 R23 G50 G52 T53 D57 V86 S88 R135 V136 L138 E156 G158 A159 T160 L161 S10 A11 L18 S19 R23 G50 G52 T53 D57 V86 S88 R135 V136 L138 E156 G158 A159 T160 L161
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0008703 5-amino-6-(5-phosphoribosylamino)uracil reductase activity
GO:0016491 oxidoreductase activity
GO:0050661 NADP binding
Biological Process
GO:0009231 riboflavin biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:5xux, PDBe:5xux, PDBj:5xux
PDBsum5xux
PubMed29864427
UniProtQ8PYN5

[Back to BioLiP]