Structure of PDB 5xu6 Chain B

Receptor sequence
>5xu6B (length=354) Species: 235443 (Cryptococcus neoformans var. grubii H99) [Search protein sequence]
TQPSDWAYIAEHIVFSYQGQSKTRALRVRNDVSGQWRRNILPKLVPRQLL
TTSREVTLEEGWYKELLRRGVLLEDLTSNVDDDGAITVAIEIKPKWGFLP
CAGHLQPPESVSIKSHVSRFRLHQHFRGRADDPPYDPLDLFSGDKMRMRT
ALDGLWTMWEISRGKSNNWKVFIGSKEISPDDLQRGLLPMGGDDLVTNIT
QLTLSALQTSSALPLLKNLQQNLDPIDISSLAALFQAEHPNSPIFDPDLI
AEVSAVELNSFVDIYISDPQAGQRMDSWSLRERIIAYALSAIFKDCSLFV
RGVLKHAEDGAWRLVSGGESVKVIDLDLKPVKNIQKWAETDEKVWKHWLK
TKGT
3D structure
PDB5xu6 Crystal structure of inositol 1,3,4,5,6-pentakisphosphate 2-kinase from Cryptococcus neoformans.
ChainB
Resolution2.35 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.1.158: inositol-pentakisphosphate 2-kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SO4 B R75 D385 R37 D325
BS02 SO4 B K389 N393 K396 W397 K329 N333 K336 W337
Gene Ontology
Molecular Function
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0035299 inositol-1,3,4,5,6-pentakisphosphate 2-kinase activity
Biological Process
GO:0016310 phosphorylation
GO:0032958 inositol phosphate biosynthetic process
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5xu6, PDBe:5xu6, PDBj:5xu6
PDBsum5xu6
PubMed28919350
UniProtJ9VKS8

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