Structure of PDB 5xtd Chain B

Receptor sequence
>5xtdB (length=176) Species: 9606 (Homo sapiens) [Search protein sequence]
TYKYVNMQDPEMDMKSVTDRAARTLLWTELFRGLGMTLSYLFREPATINY
PFEKGPLSPRFRGEHALRRYPSGEERCIACKLCEAICPAQAITIEAEPRA
DGSRRTTRYDIDMTKCIYCGFCQEACPVDAIVEGPNFEFSTETHEELLYN
KEKLLNNGDKWEAEIAANIQADYLYR
3D structure
PDB5xtd Architecture of Human Mitochondrial Respiratory Megacomplex I2III2IV2.
ChainB
Resolution3.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 7.1.1.2: NADH:ubiquinone reductase (H(+)-translocating).
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 SF4 B C111 A113 C114 K115 C117 I128 Y143 C160 A164 C77 A79 C80 K81 C83 I94 Y109 C126 A130
BS02 SF4 B H99 C121 P122 I145 C150 I151 Y152 C153 G154 F155 C156 H65 C87 P88 I111 C116 I117 Y118 C119 G120 F121 C122
BS03 PLX B T58 W61 F65 T24 W27 F31
Gene Ontology
Molecular Function
GO:0016651 oxidoreductase activity, acting on NAD(P)H
GO:0051539 4 iron, 4 sulfur cluster binding
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5xtd, PDBe:5xtd, PDBj:5xtd
PDBsum5xtd
PubMed28844695
UniProtO00217|NDUS8_HUMAN NADH dehydrogenase [ubiquinone] iron-sulfur protein 8, mitochondrial (Gene Name=NDUFS8)

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