Structure of PDB 5x7x Chain B

Receptor sequence
>5x7xB (length=77) Species: 9606 (Homo sapiens) [Search protein sequence]
NIQGITKPAIRRLARRGGVKRISGLIYEETRGVLKVFLENVIRDAVTYTE
HAKRKTVTAMDVVYALKRQGRTLYGFG
3D structure
PDB5x7x Crystal Structure and Characterization of Novel Human Histone H3 Variants, H3.6, H3.7, and H3.8
ChainB
Resolution2.184 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B T30 P32 R36 R45 T6 P8 R12 R21
BS02 dna B R35 R45 I46 S47 G48 R78 K79 T80 R11 R21 I22 S23 G24 R54 K55 T56
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Biological Process
GO:0006325 chromatin organization
GO:0006334 nucleosome assembly
GO:0032200 telomere organization
GO:0045653 negative regulation of megakaryocyte differentiation
GO:0061644 protein localization to CENP-A containing chromatin
Cellular Component
GO:0000781 chromosome, telomeric region
GO:0000786 nucleosome
GO:0005576 extracellular region
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005694 chromosome
GO:0016020 membrane
GO:0032991 protein-containing complex
GO:0043505 CENP-A containing nucleosome
GO:0070062 extracellular exosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:5x7x, PDBe:5x7x, PDBj:5x7x
PDBsum5x7x
PubMed28374988
UniProtP62805|H4_HUMAN Histone H4 (Gene Name=H4C1)

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