Structure of PDB 5x51 Chain B

Receptor sequence
>5x51B (length=1073) Species: 644223 (Komagataella phaffii GS115) [Search protein sequence]
ITTEDCWTVISAFFEEKGLVSQQLDSFDEFMETSIQDLVWEEPRLIIRFG
KIYLSRPTMTEADGTTHAMFPQEARLRNLTYSSPVYLDMEKKVHIGKVPI
MLRSKFCSLRTLDEVDLYKMKECPYDMGGYFVINGSEKVLIAQESAANIV
QVFKKAAPSPISHVAEIRSALEKGSRLISTMQIKLYGREDKGRTIKATLP
YVKQDIPIVIVFRALGVVPDGEILQHICYDENDWQMLEMLKPCIEEGFVI
QDKEVALDFIGEKRIQYAKDILQKELLPHITQEEGFETRKTFFLGYMVNR
LLLCALERKDQDDRDHFGKKLDLAGPLLANLFRILFRKLTREIYRYMQRC
IELAVKSTTITSGLKYSLATGNWGEQKKAMSSRAGVSQVLNRYTYSSTLS
HLRRTNTPIAKPRQLHNTHWGLVCPAETPEGQACGLVKNLSLLSGISIGS
PSEPIINFLEEWGMEPLEDYDPAQHTKSTRIFVNGVWTGIHRDPSMLVST
MRDLRRSGAISPEVSIIRDIREREFKIFTDVGRVYRPLFIVEDDESKDNE
LRITKEHIRKIVYGWSSLVTSGVIEYVDGEEEETIMIAMTPEDLDTAKRI
KPTFTHCEIHPSMILGVAASIIPFPDHNQSPRNTYQSAMGKQAMGVFLTN
YNVRMDTMANILYYPQKPLAKTQAMEYLKFRELPAGQNAIVAIACYSGYN
QEDSMIMNQSSIDRGLFRSLFFRSYMDQEKRFGISIVEEFEKPTRATTLR
LKHGTYEKLDEDGLIAPGVRVSGDDIIIGKTTPKRDASTPLRSTENGIVD
QVLLTTNQEGLKFVKVRMRTTKVPQIGDKFASRHGQKGTIGVTYRHEDMP
FSAEGIVPDLIINPHAIPSRMTVAHLIECLLSKVGSIRGYEGDATPFTDL
TVDAVSNLLRDNGYQSRGFEVMYNGHTGKKLMAQVFFGPTYYQRLRHMVD
DKIHARARGPVQVLTRQPVEGRSRDGGLRFGEMERDCMIAHGAAGFLKEL
MEASDAFRVHVCGICGLMSVIANLKKNQFECRSCKNKTNIYQLHIPYAAK
LLFQELMAMNIAPRLYTERSGVS
3D structure
PDB5x51 Crystal structure of RNA polymerase II from Komagataella pastoris
ChainB
Resolution6.996 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.6: DNA-directed RNA polymerase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C1163 C1166 C1185 C1012 C1015 C1034
Gene Ontology
Molecular Function
GO:0001055 RNA polymerase II activity
GO:0003677 DNA binding
GO:0003723 RNA binding
GO:0003899 DNA-directed 5'-3' RNA polymerase activity
GO:0016779 nucleotidyltransferase activity
GO:0032549 ribonucleoside binding
GO:0034062 5'-3' RNA polymerase activity
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006366 transcription by RNA polymerase II
GO:0006367 transcription initiation at RNA polymerase II promoter
GO:0140727 siRNA-mediated pericentric heterochromatin formation
Cellular Component
GO:0000428 DNA-directed RNA polymerase complex
GO:0005654 nucleoplasm
GO:0005665 RNA polymerase II, core complex
GO:0005721 pericentric heterochromatin

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5x51, PDBe:5x51, PDBj:5x51
PDBsum5x51
PubMed28412353
UniProtC4QZQ7

[Back to BioLiP]