Structure of PDB 5wzr Chain B

Receptor sequence
>5wzrB (length=630) Species: 1681 (Bifidobacterium bifidum) [Search protein sequence]
MMQFTMSGTMLRFDETTLRFSFSRDGATWSGCDGIEPQLTREDRSFSFAG
AATVTHERIETGTGVGVRSVFAGFAGADYAFETYIWIERSSGDVLCEWVP
LRECGAEPRIDRVLWPAPLSFDRADAHDVTLITHEQGVMIPNSWPTEVGT
DAVSFGGRFETAGGYMPWFAQLRSDGHAYIAICETPWNAGYDIDHPAGGP
YTHVGMWFEPSLGRMDYRRVVRYRLLDHADHTAICKTYRAYVNERGRLRT
LAEKAARNPSVRDLLGRSWVHVGIKTNVQPDSSFYDPAQPGKNDSLVTFA
QRERQMRTLHEMGAGRLYLHLDGWAQPGYDNGHPDYLPACREAGGWKGMK
SLIDACHEQGDLFGTHDQYRDYYFAARTFDPRNAIRLADGTMPEHAMWAG
GRQTYLCAELAPDYVRRNFSEIATHGIVLDCAYLDVFTCNEGDECSHPEH
RMTRRECYERRAECFEYLLAHGILTSSEEVSDWAVPSLVFCHYAPYDFQM
RSPDAPRHGIPVPLYNLVYHDCVIQPWMMDRVAGGDDYMLYALLNGGAPY
LIRDAAYAGMDGDMNAALRARTENDIERCAVVAGLHRRVGMQELVRHDLV
GGDPLVQRSVFADGTAVTCDFHAQTYEVAA
3D structure
PDB5wzr The first crystal structure of a family 129 glycoside hydrolase from a probiotic bacterium reveals critical residues and metal cofactors
ChainB
Resolution2.79 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.2.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B C407 C445 H450 C407 C445 H450
BS02 DJN B Y329 D330 D371 W398 Y433 D435 V436 E478 D561 Y329 D330 D371 W398 Y433 D435 V436 E478 D561
BS03 CA B H271 H320 D322 H366 H271 H320 D322 H366
Gene Ontology
Molecular Function
GO:0016798 hydrolase activity, acting on glycosyl bonds
GO:0033926 endo-alpha-N-acetylgalactosaminidase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5wzr, PDBe:5wzr, PDBj:5wzr
PDBsum5wzr
PubMed28546425
UniProtG5ELM1

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