Structure of PDB 5wtb Chain B

Receptor sequence
>5wtbB (length=319) Species: 158878 (Staphylococcus aureus subsp. aureus Mu50) [Search protein sequence]
NNVNDLITVTKQTIKVGDNVAAAHDGKDIEYDTEFTIDNKVKKGDTMTIN
YDKNVIPSDLTDKNDPIDITDPSGEVIAKGTFDKATKQITYTFTDYVDKY
EDIKARLTLYSYIDKQAVPNETSLNLTFATAGKETSQNVSVDYQDPMVHG
DSNIQSIFTKLDENKQTIEQQIYVNPLKKTATNTKVDIAGSQVDDYGNIK
LGNGSTIIDQNTEMKVYKVNPNQQLPQSNRIYDFSQYEDVTSQFDNKKSF
SNNVATLDFGDINSAYIIKVVSKYTPTSDGELDIAQGTSMRTTDYNYAGY
SNFIVTSNDTGGGDGTVKP
3D structure
PDB5wtb Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
ChainB
Resolution3.3 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B H299 D300 G301 P332 S333 D334 L335 T336 N339 D340 Y387 Q419 F433 Y579 S580 N581 F582 I583 V584 T585 S586 N587 H24 D25 G26 P57 S58 D59 L60 T61 N64 D65 Y112 Q144 F158 Y300 S301 N302 F303 I304 V305 T306 S307 N308
Gene Ontology
Cellular Component
GO:0005618 cell wall

View graph for
Biological Process

View graph for
Cellular Component
External links
PDB RCSB:5wtb, PDBe:5wtb, PDBj:5wtb
PDBsum5wtb
PubMed28258151
UniProtQ932F7|SDRE_STAAM Serine-aspartate repeat-containing protein E (Gene Name=sdrE)

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