Structure of PDB 5wgm Chain B

Receptor sequence
>5wgmB (length=363) Species: 7955 (Danio rerio) [Search protein sequence]
NAGGSSPITGLVYDQRMMLHHNMWDSHHPELPQRISRIFSRHEELRLLSR
CHRIPARLATEEELALCHSSKHISIIKSSEHMKPRDLNRLGDEYNSIFIS
NESYTCALLAAGSCFNSAQAILTGQVRNAVAIVRPPGHHAEKDTACGFCF
FNTAALTARYAQSITRESLRVLIVDWDVHHGNGTQHIFEEDDSVLYISLH
RYEDGAFFPNSEDANYDKVGLGKGRGYNVNIPWNGGKMGDPEYMAAFHHL
VMPIAREFAPELVLVSAGFDAARGDPLGGFQVTPEGYAHLTHQLMSLAAG
RVLIILEGGYNLTSISESMSMCTSMLLGDSPPSLDHLTPLKTSATVSINN
VLRAHAPFWSSLR
3D structure
PDB5wgm Unusual zinc-binding mode of HDAC6-selective hydroxamate inhibitors.
ChainB
Resolution1.75 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 ZN B D612 H614 D705 D177 H179 D270
BS02 AH7 B P464 S531 G582 F583 H614 F643 D705 L712 Y745 P29 S96 G147 F148 H179 F208 D270 L277 Y310
BS03 AH7 B G438 G439 S440 S441 R562 G3 G4 S5 S6 R127
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