Structure of PDB 5wfc Chain B

Receptor sequence
>5wfcB (length=769) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
EWTVDKIASALSVLAEEVPQNHSRLVNFLLEETEKRAPQPRHLSKTDPFA
HMKSKAIDGVPTMDVKFKQHSGEYGKSRNSGRRFQYPVVCIKPDREPVPI
YYFHHAEIRKNILALNSQLNPRSQKIAKRAQAEYAATLAPYLEPWLRKLN
IEGCTKSNLIRFMASQPESDDSMTPQQKSNLLDTYSDDMGSPQAVRNASM
FTEAWDRVFNDQSKLRRVALRDILMLDKNVEPIFDNKRAKLMQKVIDALG
SYTTLGCLICFSHDCEHGEIERDNQKRCFSLEEIGGLMPSLRRKWAAQIE
QHPPCRNECYRIHGVPPWSENEVGTLEWMFATIGYSQTLRPECFVGAILG
RPCWDVHRKLQEIPKQKSLPWYDRRKKQLMSDWADATITHEHAVRELFAP
CHHDGPCTAANGCPCASAGTHPVLCERFCLCTAEECPLKFTGCACHSSGK
TCLQRQGRPCICVQLNRECDPTLCKGCGARERADPENAYDEVLHSTGCQN
VALQRGAAKAVVLGKSQLEACGYGLFAAEDIEEGEFVIEYTGELISHDEG
VRREHRRGSFLFTLLEQEGIWVDAAIYGNLSRYINHATDGNIMPKIMYVN
HEWRIKFTAIKDIKAGEELFFNYGDNFPNLTKKLPLLVPKTTQPLFDPLS
KVQLLPGQPLPQHPIDDSWLLLKHRDNLQDFIDLRPEEKEFLQEWDAFIL
RRHISSEQYLPRYFLRFVREKADWLVSKRSRGEEFSKLVATLLARRVLPE
RVVIEATQVLNDARGRLRE
3D structure
PDB5wfc An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.
ChainB
Resolution2.282 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling

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Molecular Function
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Biological Process
External links
PDB RCSB:5wfc, PDBe:5wfc, PDBj:5wfc
PDBsum5wfc
PubMed29904056
UniProtG0RYC6;
G0SDW4

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