Structure of PDB 5wf7 Chain B

Receptor sequence
>5wf7B (length=765) Species: 759272 (Thermochaetoides thermophila DSM 1495) [Search protein sequence]
WTVDKIASALSVLAEEVPQNHSRLVNFLLEETEKRAPQPRHLSKTDPFAH
MKSKAIDAPEGVPTMDVKFKQHSGEYGKSRNSGRRFQYPVVCIKPDREPV
PPYRFHHAEIRKNILALNSQLNFVPPRSQKIAKRAQAEYAATLAPYLEPW
LRKLNIEGCTKSNLIRFMASDMSPQAVRNASMFTEAWDRVFNDQSKLRRV
ALRDILMLDKNVEPIFDNKRAKALMQKVIDALGSYTTLGCLICFSHDCEH
GEIERDNQKRCFSLEEIGGLMPSLRRKWAAQIEQHPPCRNECYRIHGPPW
SENEVGTLEWMFATIGYSQTLRPECFVGAILGRPCWDVHRKLQELDLPPV
EIPKQKSLPWYDRRKKQLMSDWADATITHEHAVRELFAPCHHDGPCTAAN
GCPCASAGTHPVLCERFCLCTAEECPLKFTGCACHSSGKTCLQRQGRPCI
CVQLNRECDPTLCKGCGARERADPENAYDEVLHSTGCQNVALQRGAAKAV
VLGKSQLEACGYGLFAAEDIEEGEFVIEYTGELISHDEGVRREHRRGDVN
KVSYLFTLLEQEGIWVDAAIYGNLSRYINHATDGNIMPKIMYVNHEWRIK
FTAIKDIKAGEELFFNYGDNFPNLTKKLVEPLLVPKTTQPLFDPLSKVQL
LPGQPLPQHPIDDSWLLLKHRDNLQDFIDLRPEEKEFLQEWDAFILRRHI
SSEQYLPRYFLRFVREKADWLVSKRSRGEEFSKLVATLLARRVLPERVVI
EATQVLNDARGRLRE
3D structure
PDB5wf7 An Evolutionarily Conserved Structural Platform for PRC2 Inhibition by a Class of Ezh2 Inhibitors.
ChainB
Resolution2.5 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Gene Ontology
Molecular Function
GO:0042054 histone methyltransferase activity
Biological Process
GO:0006338 chromatin remodeling

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Molecular Function
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Biological Process
External links
PDB RCSB:5wf7, PDBe:5wf7, PDBj:5wf7
PDBsum5wf7
PubMed29904056
UniProtG0RYC6;
G0SDW4

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