Structure of PDB 5wep Chain B

Receptor sequence
>5wepB (length=133) Species: 562 (Escherichia coli) [Search protein sequence]
MLQGLNHLTLAVSDLASSLAFYQQLPGMRLHASWDSGAYLSCGALWLCLS
LDEQRRKTPPQESDYTHYAFSVAEEEFAGVVALLAQAGAEVWKDNASYYF
LDPDGHKLELHVGNLAQRLAACRERPYKGMVFF
3D structure
PDB5wep Small-Molecule Inhibitor of FosA Expands Fosfomycin Activity to Multidrug-Resistant Gram-Negative Pathogens.
ChainB
Resolution3.502 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 A81 B Y65 H67 Y131 Y65 H67 Y127 PDBbind-CN: -logKd/Ki=6.36,Kd=440nM
BS02 A81 B H7 T9 Y39 W46 C48 H7 T9 Y39 W46 C48 PDBbind-CN: -logKd/Ki=6.36,Kd=440nM
BS03 ZN B H67 E113 H67 E109
Gene Ontology
Molecular Function
GO:0016740 transferase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:5wep, PDBe:5wep, PDBj:5wep
PDBsum5wep
PubMed30642934
UniProtD7UQM0

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