Structure of PDB 5wai Chain B

Receptor sequence
>5waiB (length=300) Species: 9606 (Homo sapiens) [Search protein sequence]
VQADHELFLQAFEKPTQIYRFLRTRNLIAPIFLHRTLTYMSHRNSRTNIK
RKTFKVDDMLSKVEKMKGEQESAHLQLTFTGFFHKVTLEVLLVKVCHKKR
KDVSCPIRQVPTGKQVPLNPDLNQTKPSLAVSSNEFEPSNSHMVKSYSLL
FRFVAQMTVFDKNRRLQLLDGEYEVAMQEMQGPTLQFTLRWTGRQKLRIF
YQFLYNNNTRQQTEARDDLHCPWCTLNCRKLYSLLKHLKLCHSRFIFNYV
YHPKGARIDVSINECYDFSRNGPVKRTPITHILVCRPKRTKASMSEFLEW
3D structure
PDB5wai Unique Structural Platforms of Suz12 Dictate Distinct Classes of PRC2 for Chromatin Binding.
ChainB
Resolution2.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B E84 L87 E91 T94 Q95 R98 Y430 F432 Q440 Q441 T442 E443 A444 R445 P451 W452 E6 L9 E13 T16 Q17 R20 Y201 F203 Q211 Q212 T213 E214 A215 R216 P222 W223
BS02 ZN B C450 C453 H466 H471 C221 C224 H237 H242
External links
PDB RCSB:5wai, PDBe:5wai, PDBj:5wai
PDBsum5wai
PubMed29499137
UniProtQ15022|SUZ12_HUMAN Polycomb protein SUZ12 (Gene Name=SUZ12)

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