Structure of PDB 5w7y Chain B

Receptor sequence
>5w7yB (length=103) Species: 9606 (Homo sapiens) [Search protein sequence]
GGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQL
RIKPIHTNPCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILS
IPS
3D structure
PDB5w7y Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
ChainB
Resolution2.1 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.-.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B P29 G32 P27 G30
BS02 peptide B R27 G28 P29 G32 I33 T34 K36 S39 R40 H58 N60 R25 G26 P27 G30 I31 T32 K34 S37 R38 H56 N58
Gene Ontology
Molecular Function
GO:0003906 DNA-(apurinic or apyrimidinic site) endonuclease activity
GO:0008408 3'-5' exonuclease activity
Biological Process
GO:0006302 double-strand break repair

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Molecular Function
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Biological Process
External links
PDB RCSB:5w7y, PDBe:5w7y, PDBj:5w7y
PDBsum5w7y
PubMed29059378
UniProtQ8IW19|APLF_HUMAN Aprataxin and PNK-like factor (Gene Name=APLF)

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