Structure of PDB 5w78 Chain B

Receptor sequence
>5w78B (length=406) Species: 9606 (Homo sapiens) [Search protein sequence]
DICSLPVLAKICQKIKLAMEQSVFPTLRGYHWRGRDCNDSDESVYPGRRP
NNWDVHQDSNCNGIWGVDPKDGVPYEKKFCEGSQPRGIILLGDSAGAHFH
ISPEWITASQMSLNSFINLPTALTNELDWPQLSGATGFLDSTVGIKEKSI
YLRLWKRNHCNHRDYQNISRNGASSRNLKKFIESLSRNKVLDYPAIVIYA
MIGNDVCSGKSDPVPAMTTPEKLYSNVMQTLKHLNSHLPNGSHVILYGLP
DGTFLWDNLHNRYHPLGQLNKDMTYAQLYSFLNCLQVSPCHGWMSSNKTL
RTLTSERAEQLSNTLKKIAASEKFTNFNLFYMDFAFHEIIQEWQKRGGQP
WQLIEPVDGFHPNEVALLLLADHFWKKVQLQWPQILGKENPFNPQIKQVF
GDQGGH
3D structure
PDB5w78 Crystal structure of the mammalian lipopolysaccharide detoxifier.
ChainB
Resolution2.271 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.1.1.77: acyloxyacyl hydrolase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D205 N207 D208 D210 V213 D36 N38 D39 D41 V44
BS02 CA B D223 D227 N229 N231 I233 E245 D54 D58 N60 N62 I64 E76
Gene Ontology
Molecular Function
GO:0016788 hydrolase activity, acting on ester bonds
GO:0050528 acyloxyacyl hydrolase activity

View graph for
Molecular Function
External links
PDB RCSB:5w78, PDBe:5w78, PDBj:5w78
PDBsum5w78
PubMed29343645
UniProtP28039|AOAH_HUMAN Acyloxyacyl hydrolase (Gene Name=AOAH)

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