Structure of PDB 5w3h Chain B

Receptor sequence
>5w3hB (length=427) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence]
MREIIHISTGQCGNQIGAAFWETICGEHGLDFNGTYHGHDDIQKERLNVY
FNEASSGKWVPRSINVDLEPGTIDAVRNSAIGNLFRPDNYIFGQSSAGNV
WAKGHYTEGAELVDSVMDVIRREAEGCDSLQGFQITHSLGGGTGSGMGTL
LISKIREEFPDRMMATFSVLPSPKTSDTVVEPYNATLSVHQLVEHSDETF
CIDNEALYDICQRTLKLNQPSYGDLNNLVSSVMSGVTTSLRYPGQLNSDL
RKLAVNLVPFPRLHFFMVGYAPLTAIGSQSFRSLTVPELTQQMFDAKNMM
AAADPRNGRYLTVAAFFRGKVSVKEVEDEMHKVQSKNSDYFVEWIPNNVQ
TAVCSVAPQGLDMAATFIANSTSIQELFKRVGDQFSAMFKRKAFLHWYTS
EGMDELEFSEAESNMNDLVSEYQQYQE
3D structure
PDB5w3h Structural differences between yeast and mammalian microtubules revealed by cryo-EM.
ChainB
Resolution4.0 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GDP B Q11 C12 Q15 S138 T143 N204 Y222 N226 Q11 C12 Q15 S138 T143 N204 Y222 N226
BS02 EP B L215 L217 D224 P272 L273 T274 I276 R282 L215 L217 D224 P272 L273 T274 I276 R282
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
GO:0005525 GTP binding
GO:0046872 metal ion binding
Biological Process
GO:0000022 mitotic spindle elongation
GO:0000226 microtubule cytoskeleton organization
GO:0000278 mitotic cell cycle
GO:0007010 cytoskeleton organization
GO:0007017 microtubule-based process
GO:0031122 cytoplasmic microtubule organization
GO:0046677 response to antibiotic
GO:0090307 mitotic spindle assembly
GO:0090316 positive regulation of intracellular protein transport
Cellular Component
GO:0005737 cytoplasm
GO:0005856 cytoskeleton
GO:0005874 microtubule
GO:0045298 tubulin complex

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5w3h, PDBe:5w3h, PDBj:5w3h
PDBsum5w3h
PubMed28652389
UniProtP02557|TBB_YEAST Tubulin beta chain (Gene Name=TUB2)

[Back to BioLiP]