Structure of PDB 5w0o Chain B

Receptor sequence
>5w0oB (length=317) Species: 9606 (Homo sapiens) [Search protein sequence]
PLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDFPGTK
LSLFGSSKNGFGFKQSDLDVCMTINGLGLDCVRTIEELARVLRKHSGLRN
ILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAYSAIDPRVK
YLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPPVIPVLQEI
YKKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWLGLLRFYTEE
FDFKEHVISIRRKSLLTTFKKQWTSIVIEDPFDLNHNLGAGLSRKMTNFI
MKAFINGRRVFEYFFDP
3D structure
PDB5w0o Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
ChainB
Resolution2.488 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B L1097 I1099 R1165 L102 I104 R170
BS02 rna B I1099 T1101 A1102 K1103 V1104 N1124 A1163 S1164 G1291 I104 T106 A107 K108 V109 N129 A168 S169 G291
BS03 UTP B F1045 G1046 S1047 S1057 N1130 S1170 Y1171 F54 G55 S56 S66 N135 S175 Y176
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0o, PDBe:5w0o, PDBj:5w0o
PDBsum5w0o
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

[Back to BioLiP]