Structure of PDB 5w0m Chain B

Receptor sequence
>5w0mB (length=350) Species: 9606 (Homo sapiens) [Search protein sequence]
EPLPPLTPKFLNILDQVCIQCYKDFSPTIIEDQAREHIRQNLESFIRQDF
PGTKLSLFGSSKNGFGFKQSDLAVCMTINGLETAEGLDCVRTIEELARVL
RKHSGLRNILPITTAKVPIVKFFHLRSGLEVDISLYNTLALHNTRLLSAY
SAIDPRVKYLCYTMKVFTKMCDIGDASRGSLSSYAYTLMVLYFLQQRNPP
VIPVLQEIYKGKPEIFVDGWNIYFFDQIDELPTYWSECGKNTESVGQLWL
GLLRFYTEEFDFKEHVISIRRKSLLTTFKKQWTSKYIVIEDPFDLNHNLG
AGLSRKMTNFIMKAFINGRRVFGIPVSKMEYFFDPDVLTEGELAPNDRCC
3D structure
PDB5w0m Multi-domain utilization by TUT4 and TUT7 in control of let-7 biogenesis.
ChainB
Resolution2.298 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.52: RNA uridylyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 rna B F1045 G1046 T1101 A1102 K1103 V1104 N1124 N1130 A1163 S1164 L1288 A1290 F58 G59 T114 A115 K116 V117 N137 N143 A176 S177 L299 A301
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0008270 zinc ion binding

View graph for
Molecular Function
External links
PDB RCSB:5w0m, PDBe:5w0m, PDBj:5w0m
PDBsum5w0m
PubMed28671666
UniProtQ5VYS8|TUT7_HUMAN Terminal uridylyltransferase 7 (Gene Name=TUT7)

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