Structure of PDB 5vzu Chain B

Receptor sequence
>5vzuB (length=418) Species: 9606 (Homo sapiens) [Search protein sequence]
SGRSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCR
EEYGVCENLRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNV
VVDGLFIIGWMYLPPHDPHVDDPMRFKPLFRIHLMERKAATVECMYGHKG
PHHGHIQIVKKDEFSTKCNQTDHHRMSGGRQEEFRTWLREEWGRTLEDIF
HEHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLIKPGLFKGTYGSH
GLEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQRN
FNELSRIVLEVRERVRQEQQEGQPFVLPVGVSSRNEDYPRTCRMCFYGTG
LIAGHGFTSPERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADA
PSPQAFDEMLKNIQSLTS
3D structure
PDB5vzu Structural basis of the phosphorylation-independent recognition of cyclin D1 by the SCFFBXO31 ubiquitin ligase.
ChainB
Resolution2.7 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B H265 Y309 H312 K330 D334 N336 I337 S453 I473 A474 W500 L503 H203 Y247 H250 K268 D272 N274 I275 S332 I352 A353 W379 L382
BS02 ZN B C206 H214 C230 H236 C144 H152 C168 H174
External links
PDB RCSB:5vzu, PDBe:5vzu, PDBj:5vzu
PDBsum5vzu
PubMed29279382
UniProtQ5XUX0|FBX31_HUMAN F-box only protein 31 (Gene Name=FBXO31)

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