Structure of PDB 5vqi Chain B

Receptor sequence
>5vqiB (length=421) Species: 5141 (Neurospora crassa) [Search protein sequence]
DLPKMVEGVFSSEIDKQIQATTKFRKLLSKERNPPIEEVIKTGVVGRFVE
FLRSPHTLVQFEAAWALTNIASGSATQTQVVIEAGAVPIFVELLGSPEPD
VREQAVWALGNIAGDSPQCRDYVLSCGALRPLLTLLGDSRKLSMLRNATW
TLSNFCRGKTPQPDWNTIAPALPVLAKLVYSLDDEVLIDACWAISYLSDG
SNDKIQAVIEAGIPRRLVELLMHASTSVQTPALRSVGNIVTGDDVQTQVI
INCGALPCLLSLLSSNKDGIRKEACWTISNITAGNSAQIQSVIDANIIPP
LIHLLSHADLKTRKEACWAISNATSGGLQKPDQIRYLVAQGCIKPLCDLL
ACPDNKIIQVALDGLENILKVGELDKNAASINRYALFIEECGGMEKIHDC
QTNANEEIYMKAYNIIEKYFS
3D structure
PDB5vqi Nuclear transport of the Neurospora crassa NIT-2 transcription factor is mediated by importin-alpha.
ChainB
Resolution2.501 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B S110 K111 F142 W146 N150 A152 S153 Q185 W188 N192 G195 D196 W231 N235 S29 K30 F61 W65 N69 A71 S72 Q104 W107 N111 G114 D115 W150 N154
BS02 peptide B R315 N319 T328 E354 W357 N361 A364 E396 W399 R234 N238 T247 E273 W276 N280 A283 E315 W318
Gene Ontology
Molecular Function
GO:0061608 nuclear import signal receptor activity
Biological Process
GO:0006606 protein import into nucleus
Cellular Component
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vqi, PDBe:5vqi, PDBj:5vqi
PDBsum5vqi
PubMed29054975
UniProtQ9C2K9

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