Structure of PDB 5vbz Chain B

Receptor sequence
>5vbzB (length=164) Species: 9606 (Homo sapiens) [Search protein sequence]
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIEDSYRKQVVIDGET
CLLDILDTAGEYSAMRDQYCRTGEGFLCVFAINNTKSFEDIHQYREQIKR
VKDSDDVPMVLVGNKCDLAARTVESRQAQDLARSYGIPYIETSAKTRQGV
EDAFYTLVREIRQH
3D structure
PDB5vbz Ras Binder Induces a Modified Switch-II Pocket in GTP and GDP States.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.5.2: small monomeric GTPase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GNP B G13 G15 K16 S17 A18 F28 V29 D30 G60 N116 K117 D119 L120 S145 A146 G13 G15 K16 S17 A18 F28 V29 D30 G60 N114 K115 D117 L118 S143 A144
Gene Ontology
Molecular Function
GO:0003924 GTPase activity
GO:0005525 GTP binding
Biological Process
GO:0007165 signal transduction
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5vbz, PDBe:5vbz, PDBj:5vbz
PDBsum5vbz
PubMed29033317
UniProtP01112|RASH_HUMAN GTPase HRas (Gene Name=HRAS)

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