Structure of PDB 5vau Chain B

Receptor sequence
>5vauB (length=137) Species: 9606 (Homo sapiens) [Search protein sequence]
DNREIVMKYIHYKLSQRGYEWDESEVVHLTLRQAGDDFSRRYRRDFAEMS
SQLHLTPFTARGRFATVVEELFRDGVNWGRIVAFFEFGGVMCVESVNREM
SPLVDNIALWMTEYLNRHLHTWIQDNGGWDAFVELYG
3D structure
PDB5vau Bcl-2 complex with Beclin 1 BH3 domain
ChainB
Resolution1.754 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B D103 F104 R107 Y108 F112 M115 R129 T132 V133 E136 L137 D140 N143 G145 R146 F153 L201 Y202 D37 F38 R41 Y42 F46 M49 R63 T66 V67 E70 L71 D74 N77 G79 R80 F87 L135 Y136
Gene Ontology
Biological Process
GO:0042981 regulation of apoptotic process

View graph for
Biological Process
External links
PDB RCSB:5vau, PDBe:5vau, PDBj:5vau
PDBsum5vau
PubMed
UniProtP10415|BCL2_HUMAN Apoptosis regulator Bcl-2 (Gene Name=BCL2)

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