Structure of PDB 5v4b Chain B

Receptor sequence
>5v4bB (length=444) Species: 9606 (Homo sapiens) [Search protein sequence]
TQVKHMMQVIEPQFQRDFISLLPKELALYVLSFLEPKDLLQAAQTCRYWR
ILAEDNLLWREKCKEEGIDEPLHIKRRKVIKPGFIHSPWKSAYIRQHRID
TNWRRGELKSPKVLKGHDDHVITCLQFCGNRIVSGSDDNTLKVWSAVTGK
CLRTLVGHTGGVWSSQMRDNIIISGSTDRTLKVWNAETGECIHTLYGHTS
TVRCMHLHEKRVVSGSRDATLRVWDIETGQCLHVLMGHVAAVRCVQYDGR
RVVSGAYDFMVKVWDPETETCLHTLQGHTNRVYSLQFDGIHVVSGSLDTS
IRVWDVETGNCIHTLTGHQSLTSGMELKDNILVSGNADSTVKIWDIKTGQ
CLQTLQGPNKHQSAVTCLQFNKNFVITSSDDGTVKLWDLKTGEFIRNLVT
LESGGSGGVVWRIRASNTKLVCAVGSRNGTEETKLLVLDFDVDM
3D structure
PDB5v4b FBXW7 regulates DISC1 stability via the ubiquitin-proteosome system.
ChainB
Resolution2.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B W2425 S2462 R2465 R2479 Y2519 A2626 W163 S200 R203 R217 Y257 A364
External links
PDB RCSB:5v4b, PDBe:5v4b, PDBj:5v4b
PDBsum5v4b
PubMed28727686
UniProtQ969H0|FBXW7_HUMAN F-box/WD repeat-containing protein 7 (Gene Name=FBXW7)

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