Structure of PDB 5v3y Chain B

Receptor sequence
>5v3yB (length=273) Species: 1773 (Mycobacterium tuberculosis) [Search protein sequence]
QIDGFVRTLRARPGKVPVFVFHPAGGSTVVYEPLLGRLPADTPMYGFERV
EGSIEERAQQYVPKLIEMQGDGPYVLVGWSLGGVLAYACAIGLRRLGKDV
RFVGLIDAVRAGEEIPQTKEEIRKRWDRYAAFAEKTFNVTIPAIPYEQLE
ELDDEGQVRFVLDAVSQSGVQIPAGIIEHQRTSYLDNRAIDTAQIQPYDG
HVTLYMADRYHDDAIMFEPRYAVRQPDGGWGEYVSDLEVVPIGGEHIQAI
DEPIIAKVGEHMSRALGQIEADR
3D structure
PDB5v3y Development of a Novel Lead that Targets M. tuberculosis Polyketide Synthase 13.
ChainB
Resolution1.98 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 5V8 B Y1582 Q1633 S1636 Y1637 N1640 D1644 Y1663 D1666 A1667 F1670 Y1674 Y129 Q180 S183 Y184 N187 D191 Y210 D213 A214 F217 Y221 MOAD: ic50=0.19uM
BindingDB: IC50=0.190000nM
Gene Ontology
Biological Process
GO:0009058 biosynthetic process

View graph for
Biological Process
External links
PDB RCSB:5v3y, PDBe:5v3y, PDBj:5v3y
PDBsum5v3y
PubMed28669536
UniProtI6X8D2|PKS13_MYCTU Polyketide synthase Pks13 (Gene Name=pks13)

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