Structure of PDB 5v3a Chain B

Receptor sequence

>5v3aB (length=154) Species: 487 (Neisseria meningitidis)

RQLPSHELIMSELMMPDTANFSGNVHGGELLLLLDQVAYSCASRYSGNYC
VTLSVDKVLFKEPIHIGDLVTFYAAVNYTGRTSMEIGIRVEAQNIRTGEI
RHTNSCYFTMVAVKDGKPVPVPPLEILTDRQRCRYEKAKKRRDISLQASE
DMSC

3D structure

• PDB: 5v3a Structural insights into GDP-mediated regulation of a bacterial acyl-CoA thioesterase.
• Chain: B
• Resolution: 2.0 Å

Enzymatic activity

• Enzyme Commision number: 3.1.2.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	COA	B	V29 G31 L34 F64 K65 E66 P67	V25 G27 L30 F60 K61 E62 P63
BS02	GDP	B	D155 S157 C158	D151 S153 C154
BS03	COA	B	V55 T56 L57 G84 R85 T86 S87 V115 R146 S149	V51 T52 L53 G80 R81 T82 S83 V111 R142 S145
BS04	GDP	B	E11 Y77 A78 A79 N81 G91 I92 R93 H106 S109 Y111 R138	E7 Y73 A74 A75 N77 G87 I88 R89 H102 S105 Y107 R134

Gene Ontology

Molecular Function

• GO:0016787 hydrolase activity
• GO:0016790 thiolester hydrolase activity

External links

• PDB: RCSB:5v3a, PDBe:5v3a, PDBj:5v3a
• PDBsum: 5v3a
• PubMed: 28972175
• UniProt: A0A0Y5D4F5