Structure of PDB 5v0l Chain B

Receptor sequence
>5v0lB (length=166) Species: 10090 (Mus musculus) [Search protein sequence]
RHRDRLNTELDRLASLLPFPQDVINKLDKLSVLRLSVSYLRAKSFFDVAL
KSTQEGEFLLQALVLVVTADALVFYASSTIQDYLGFQQSDVIHQSVYELI
HTEDRAEFQRQLHWALDQLPPENASFMERCFRCDNSSGFLAMNFQGRLKY
LHLPPQLALFAIATPL
3D structure
PDB5v0l Structural hierarchy controlling dimerization and target DNA recognition in the AHR transcriptional complex.
ChainB
Resolution4.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna B R37 H38 R39 R1 H2 R3 PDBbind-CN: Kd=4.86nM
BS02 dna B R39 K65 R3 K29 PDBbind-CN: Kd=4.86nM
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
GO:0046983 protein dimerization activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
GO:0006805 xenobiotic metabolic process
GO:0009410 response to xenobiotic stimulus
Cellular Component
GO:0005634 nucleus
GO:0005667 transcription regulator complex
GO:0005737 cytoplasm

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External links
PDB RCSB:5v0l, PDBe:5v0l, PDBj:5v0l
PDBsum5v0l
PubMed28396409
UniProtP30561|AHR_MOUSE Aryl hydrocarbon receptor (Gene Name=Ahr)

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