Structure of PDB 5v02 Chain B

Receptor sequence
>5v02B (length=87) Species: 9606 (Homo sapiens) [Search protein sequence]
GRKLELTKADTQLTKRVKNAAANVLRETWLIYKNTKLVKKIDHAKVRKHQ
RKFLQAIHQLRSVKMEQRKLNDQANTLVDLAKTQLEH
3D structure
PDB5v02 An Intracellular Allosteric Modulator Binding Pocket in SK2 Ion Channels Is Shared by Multiple Chemotypes.
ChainB
Resolution1.78 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 657 B A477 L480 V481 A74 L77 V78
Gene Ontology
Molecular Function
GO:0005516 calmodulin binding
GO:0015269 calcium-activated potassium channel activity
GO:0016286 small conductance calcium-activated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:5v02, PDBe:5v02, PDBj:5v02
PDBsum5v02
PubMed29576321
UniProtQ9H2S1|KCNN2_HUMAN Small conductance calcium-activated potassium channel protein 2 (Gene Name=KCNN2)

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