Structure of PDB 5uvx Chain B

Receptor sequence
>5uvxB (length=105) Species: 9606 (Homo sapiens) [Search protein sequence]
QLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMST
IKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEM
RFAKM
3D structure
PDB5uvx BRD4 Bromodomain 2 with A-1359643
ChainB
Resolution1.53 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8NM B W374 P375 K378 P379 V380 D381 L385 N433 V439 M442 W22 P23 K26 P27 V28 D29 L33 N81 V87 M90 BindingDB: Ki=2.4nM,EC50=11nM
External links
PDB RCSB:5uvx, PDBe:5uvx, PDBj:5uvx
PDBsum5uvx
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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