Structure of PDB 5us1 Chain B

Receptor sequence
>5us1B (length=178) Species: 588 (Providencia stuartii) [Search protein sequence]
MGIEYRSLHTSQLTLSEKEALYDLLIEGFEGDFSHDDFAHTLGGMHVMAF
DQQKLVGHVAIIQRHMALDNTPISVGYVEAMVVEQSYRRQGIGRQLMLQT
NKIIASCYQLGLLSASDDGQKLYHSVGWQIWKGKLFELKQGSYIRSIEEE
GGVMGWKADGEVDFTASLYCDFRGGDQW
3D structure
PDB5us1 Plazomicin Retains Antibiotic Activity against Most Aminoglycoside Modifying Enzymes.
ChainB
Resolution2.48 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.3.1.59: gentamicin 2'-N-acetyltransferase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8MM B D32 D37 S114 A115 S116 D117 E149 W178 D32 D37 S114 A115 S116 D117 E149 W178
Gene Ontology
Molecular Function
GO:0016746 acyltransferase activity
GO:0016747 acyltransferase activity, transferring groups other than amino-acyl groups
GO:0047921 aminoglycoside 2'-N-acetyltransferase activity
Biological Process
GO:0046677 response to antibiotic

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Molecular Function
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Biological Process
External links
PDB RCSB:5us1, PDBe:5us1, PDBj:5us1
PDBsum5us1
PubMed29634241
UniProtQ52424|AAC2_PROST Aminoglycoside 2'-N-acetyltransferase (Gene Name=aac)

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