Structure of PDB 5uqa Chain B

Receptor sequence
>5uqaB (length=30) Species: 9606 (Homo sapiens) [Search protein sequence]
FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB5uqa Insulin with proline analog FzP at position B28 in the R6 state
ChainB
Resolution1.31 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B C7 L11 L15 C19 R22 G23 F24 Y26 C7 L11 L15 C19 R22 G23 F24 Y26
BS02 peptide B H5 G8 S9 V12 E13 Y16 G20 E21 G23 F24 F25 Y26 T27 X28 H5 G8 S9 V12 E13 Y16 G20 E21 G23 F24 F25 Y26 T27 X28
BS03 peptide B V2 H5 V2 H5
BS04 peptide B L6 H10 L6 H10
Gene Ontology
Molecular Function
GO:0005179 hormone activity
Cellular Component
GO:0005576 extracellular region

View graph for
Molecular Function

View graph for
Cellular Component
External links
PDB RCSB:5uqa, PDBe:5uqa, PDBj:5uqa
PDBsum5uqa
PubMed
UniProtP01308|INS_HUMAN Insulin (Gene Name=INS)

[Back to BioLiP]