Structure of PDB 5uqa Chain B
Receptor sequence
>5uqaB (length=30) Species:
9606
(Homo sapiens) [
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FVNQHLCGSHLVEALYLVCGERGFFYTPKT
3D structure
PDB
5uqa
Insulin with proline analog FzP at position B28 in the R6 state
Chain
B
Resolution
1.31 Å
3D
structure
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Enzymatic activity
Enzyme Commision number
?
Interaction with ligand
Site
#
Ligand
Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01
peptide
B
C7 L11 L15 C19 R22 G23 F24 Y26
C7 L11 L15 C19 R22 G23 F24 Y26
BS02
peptide
B
H5 G8 S9 V12 E13 Y16 G20 E21 G23 F24 F25 Y26 T27 X28
H5 G8 S9 V12 E13 Y16 G20 E21 G23 F24 F25 Y26 T27 X28
BS03
peptide
B
V2 H5
V2 H5
BS04
peptide
B
L6 H10
L6 H10
Gene Ontology
Molecular Function
GO:0005179
hormone activity
Cellular Component
GO:0005576
extracellular region
View graph for
Molecular Function
View graph for
Cellular Component
External links
PDB
RCSB:5uqa
,
PDBe:5uqa
,
PDBj:5uqa
PDBsum
5uqa
PubMed
UniProt
P01308
|INS_HUMAN Insulin (Gene Name=INS)
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