Structure of PDB 5uph Chain B

Receptor sequence
>5uphB (length=324) Species: 9606 (Homo sapiens) [Search protein sequence]
DSWEKPPLPVYTQFYFFNVTNPEEILRGETPRVEEVGPYTYRELRNVSNK
AYVFERDQSVGDPKIDLIRTLNIPVLTVIEWSQVHFLREIIEAMLKAYQQ
KLFVTHTVDELLWGYKDEILSLIHVFRPDISPYFGLFYEKNGTNDGDYVF
LTGEDFTKIVEWNGKTSHPLITKDEVLYVFPSDFCRSVYITFSDYESVQG
LPAFRYKVPAEICLGSGVLNVSICKNGAPIIMSFPHFYQADERFVSAIEG
MHPNQEDHETFVDINPLTGIILKAAKRFQINIYVKKLDDFVETGDIRTMV
FPVMYLNESVHIDKETASRLKSMI
3D structure
PDB5uph Lysosomal integral membrane protein-2 as a phospholipid receptor revealed by biophysical and cellular studies.
ChainB
Resolution3.0 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 M6D B R275 N325 R186 N220
BS02 CLR B V60 E230 V268 T365 V367 I376 K381 V10 E161 V179 T260 V262 I271 K276
Gene Ontology
Molecular Function
GO:0005044 scavenger receptor activity
Cellular Component
GO:0005764 lysosome
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5uph, PDBe:5uph, PDBj:5uph
PDBsum5uph
PubMed29199275
UniProtQ14108|SCRB2_HUMAN Lysosome membrane protein 2 (Gene Name=SCARB2)

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