Structure of PDB 5ung Chain B

Receptor sequence
>5ungB (length=410) Species: 562,9606 [Search protein sequence]
ADLEDNWETLNDNLKVIEKADNAAQVKDALTKMRAAALDAQKATPPKLED
KSPDSPEMKDFRHGFDILVGQIDDALKLANEGKVKEAQAAAEQLKTTRNA
YIQKYLGSGSCSQKPSDKHLDAIPILYYIIFVIGFLVNIVVVTLFCCQKG
PKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVFGSFL
TLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLS
SLPTFYFRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPL
IFIATCYFGIRKHLLKTNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHV
LTFLDALAWMGVINSCEVIAVIDLALPFAILLGFTNSCVNPFLYCFVGNR
FQQKLRSVFR
3D structure
PDB5ung Structural basis for selectivity and diversity in angiotensin II receptors.
ChainB
Resolution2.8 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 8ES B Y51 W100 Y103 Y104 L124 T125 M128 F129 T178 R182 K215 F272 I304 F308 Y127 W176 Y179 Y180 L200 T201 M204 F205 T254 R258 K291 F348 I380 F384 PDBbind-CN: -logKd/Ki=9.47,Ki=0.34nM
Gene Ontology
Molecular Function
GO:0004930 G protein-coupled receptor activity
GO:0004945 angiotensin type II receptor activity
GO:0005506 iron ion binding
GO:0009055 electron transfer activity
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0006954 inflammatory response
GO:0007186 G protein-coupled receptor signaling pathway
GO:0022900 electron transport chain
GO:0042981 regulation of apoptotic process
GO:0097746 blood vessel diameter maintenance
Cellular Component
GO:0016020 membrane
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ung, PDBe:5ung, PDBj:5ung
PDBsum5ung
PubMed28379944
UniProtP0ABE7|C562_ECOLX Soluble cytochrome b562 (Gene Name=cybC);
P50052|AGTR2_HUMAN Type-2 angiotensin II receptor (Gene Name=AGTR2)

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