Structure of PDB 5un1 Chain B

Receptor sequence
>5un1B (length=397) Species: 8355 (Xenopus laevis) [Search protein sequence]
DEHLSIVTLEEAPFVIVEDVDPLSGTCMRNTVPCRKQGNYIKRCCKGFCI
DILKKIAKTVKFTYDLYLVTNGKHGKKINGVWNGMIGEVVTKRAYMAVGS
LTINEERSEVVDFSVPFIETGISVMVSAFLEPFSADVWVMMFVMLLIVSA
VAVFVFEPSFTIGKAIWLLWGLVFNNSLPVQNPKGTTSKIMVSVWAFFAV
IFLASYTANLAAFMIQGLSDKKFQRPNDFSPAFRFGTVPNGSTERNIRNN
YLEMHSYMVKFNQRSVQDALLSLKSGKLDAFIYDAAVLNYMAGRDEGCKL
VTIGSGKVFATTGYGIAIQKDSGWKRQVDLAILQLFGDGEMEELEALWLT
GICHNEKNEVMSSQLDIDNMAGVFYMLAAAMALSLITFIMEHLFYKS
3D structure
PDB5un1 Mechanism of NMDA receptor channel block by MK-801 and memantine.
ChainB
Resolution3.6 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 GLU B H479 G480 S505 L506 T507 R512 S673 H74 G75 S100 L101 T102 R107 S242
BS02 BMK B L626 T630 L203 T207
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0015276 ligand-gated monoatomic ion channel activity
GO:0038023 signaling receptor activity
Biological Process
GO:0006811 monoatomic ion transport
Cellular Component
GO:0016020 membrane

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5un1, PDBe:5un1, PDBj:5un1
PDBsum5un1
PubMed29670280
UniProtA7XY94|NMDE2_XENLA Glutamate receptor ionotropic, NMDA 2B (Gene Name=grin2b)

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