Structure of PDB 5ulj Chain B

Receptor sequence
>5uljB (length=386) Species: 322104 (Scheffersomyces stipitis CBS 6054) [Search protein sequence]
LVPRGSHMMKTLSLQSRAKKQPKEIFAFARDIDGEFVYDQKIVKDENVSY
YYLPDSKIDGSIDLQAGYAKFKKIPEEKNMSDMKCLLTALTKYEQEHNNG
EKVNVDIITYRGLMTKLLALPYNLNDPVDLNVLAYDGQLFINSDEEIELA
RRKEEDEHKQQSMTPEKYDHMKRCEFSGYKFEAIATLPKPWAKKMVNNYE
QYISVIKTGIGEAKMLLAGEVDCVWDYIPEDGKDVLSHYMELKTTRILES
NGQVVNFEKKLFKTWAQCFLMGIRKVVYGFRDDSFFLRDVELYKTEEIPL
LIKNNALTENKSGGKINCTTALKWYGAVIEWLLQEIPRDDTSKAYRVSFD
PSTRTFTLRELMGNENSRLRNGEMLTSEFKQWRESI
3D structure
PDB5ulj 5' End Nicotinamide Adenine Dinucleotide Cap in Human Cells Promotes RNA Decay through DXO-Mediated deNADding.
ChainB
Resolution1.911 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.6.1.-
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 CA B D230 E249 L250 D222 E241 L242
BS02 0WD B N76 M77 Y107 R108 G109 S140 E145 Y176 Q209 G227 E228 K251 N79 M80 Y110 R111 G112 S143 E148 Y179 Q201 G219 E220 K243
Gene Ontology
Molecular Function
GO:0000166 nucleotide binding
GO:0003723 RNA binding
GO:0004518 nuclease activity
GO:0034353 mRNA 5'-diphosphatase activity
GO:0046872 metal ion binding
Biological Process
GO:0000956 nuclear-transcribed mRNA catabolic process
GO:0006397 mRNA processing
GO:0110155 NAD-cap decapping
Cellular Component
GO:0005634 nucleus
GO:0005829 cytosol

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5ulj, PDBe:5ulj, PDBj:5ulj
PDBsum5ulj
PubMed28283058
UniProtA3LNL5|DXO_PICST Decapping nuclease RAI1 (Gene Name=RAI1)

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