Structure of PDB 5uk5 Chain B

Receptor sequence
>5uk5B (length=308) Species: 10116 (Rattus norvegicus) [Search protein sequence]
ADPRLGQFELEILSMQNVNGELQNGNCCGGARNPGDRKCTGDECNTYFKV
CLKEYQSRVRAGGPCSFGSGSTPVIGGNTFNLKASRGNDRNRIVLPFSFA
WPRSYTLLVEAWDSSNDTIQPDSIIEKASHSGMINPSRQWQTLKQNTGIA
HFEYRIRVTCDDHYYGFGCNKFCRPRDDFFGHYACDQNGNKTCMEGWMGP
ECNKAICRQGCSPKHGSCKLPGDCRCQYGWQGLYCDKCIPHPGCVHGTCN
EPWQCLCETNWGGQLCDKDLNYCGTHQPCLNRGTCSNTGPDKYQCSCPEG
YSGPNCEA
3D structure
PDB5uk5 Notch-Jagged complex structure implicates a catch bond in tuning ligand sensitivity.
ChainB
Resolution2.506 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 FUC B E81 Y82 E54 Y55
BS02 FUC B R309 T311 R282 T284
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
Biological Process
GO:0007154 cell communication
GO:0007219 Notch signaling pathway
GO:0007275 multicellular organism development
Cellular Component
GO:0016020 membrane

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Molecular Function
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Cellular Component
External links
PDB RCSB:5uk5, PDBe:5uk5, PDBj:5uk5
PDBsum5uk5
PubMed28254785
UniProtQ63722|JAG1_RAT Protein jagged-1 (Gene Name=Jag1)

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