Structure of PDB 5ufs Chain B

Receptor sequence
>5ufsB (length=248) Species: 32644 (unidentified) [Search protein sequence]
APTLISLLEVIEPEVLYSGYDSTLPDTSTRLMSTLNRLGGRQVVSAVKWA
KALPGFRNLHLDDQMTLLQYSWMSLMAFSLGWRSYKQSNGNMLCFAPDLV
INEERMQLPYMYDQCQQMLKISSEFVRLQVSYDEYLCMKVLLLLSTVPKD
GLKSQAVFDEIRMTYIKELGKAIVKREGNSSQNWQRFYQLTKLLDSMHEM
VGGLLQFCFYTFVNKSLSVEFPEMLAEIISNQLPKFKAGSVKPLLFHQ
3D structure
PDB5ufs Structural Analysis of the Glucocorticoid Receptor Ligand-Binding Domain in Complex with Triamcinolone Acetonide and a Fragment of the Atypical Coregulator, Small Heterodimer Partner.
ChainB
Resolution2.118 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B V44 K48 L58 M62 E220 M221 E224 V47 K51 L61 M65 E223 M224 E227
BS02 1TA B M29 L32 N33 Q39 M70 M73 F92 M108 Q111 F204 T208 M32 L35 N36 Q42 M73 M76 F95 M111 Q114 F207 T211 MOAD: Ki=3.2nM
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
GO:0034056 estrogen response element binding
Biological Process
GO:0006357 regulation of transcription by RNA polymerase II
GO:0030518 nuclear receptor-mediated steroid hormone signaling pathway

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Molecular Function
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Biological Process
External links
PDB RCSB:5ufs, PDBe:5ufs, PDBj:5ufs
PDBsum5ufs
PubMed28396564
UniProtA0A1X8XLE9

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