Structure of PDB 5ueo Chain B

Receptor sequence
>5ueoB (length=109) Species: 9606 (Homo sapiens) [Search protein sequence]
SHMEQLKCCSGILKEMFAKKHAAYAWPFYKPVDVEALGLHDYCDIIKHPM
DMSTIKSKLEAREYRDAQEFGADVRLMFSNCYKYNPPDHEVVAMARKLQD
VFEMRFAKM
3D structure
PDB5ueo Complex structure of BRD4_BD2_A-1395017
ChainB
Resolution1.85 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 87G B W374 P375 P379 V380 D381 L385 N433 H437 V439 M442 W26 P27 P31 V32 D33 L37 N85 H89 V91 M94 BindingDB: EC50=56nM,Ki=11nM
External links
PDB RCSB:5ueo, PDBe:5ueo, PDBj:5ueo
PDBsum5ueo
PubMed
UniProtO60885|BRD4_HUMAN Bromodomain-containing protein 4 (Gene Name=BRD4)

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