Structure of PDB 5u84 Chain B

Receptor sequence
>5u84B (length=353) Species: 9767 (Balaenoptera acutorostrata) [Search protein sequence]
DCRKSTYPPSGPTYRGPVPWYTINLDLPPYKRWHELMVDKAPALKVIVNY
LKNMINAFEPSGKIVQLVDQKLPGLLGSFPGPFEEEMKGIAAVTEIPLGE
IILFNIFYEFFTIATSIITEDKEGHLLHARNMDFGVFLGWNVNNNTWVVT
EELKPLTVNLDFQRNSKTVFKAAGFAGYVGMLTGFKPGLFSLTLNERFSG
FMGVIEWIFIIRSVLENSTSYEEAKTILTKSKILAPAYFILGGSKSGEGC
VITRDRVQSLDIYELDPKQGIWYVVQTNYDRWKNPFFLDNRRTPAKMCLN
RTTQENISFATMYDVLSTKPVLNKLTVYTALIDVTKGQFETYLRDCPDPC
IGW
3D structure
PDB5u84 Structural basis for the activation of acid ceramidase.
ChainB
Resolution2.34 Å
3D
structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]
Enzymatic activity
Enzyme Commision number 3.5.1.-
3.5.1.23: ceramidase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 I3C B S350 F351 K378 Q380 S308 F309 K336 Q338
BS02 I3C B H154 D375 T377 K378 H125 D333 T335 K336
Gene Ontology
Molecular Function
GO:0016787 hydrolase activity
GO:0017040 N-acylsphingosine amidohydrolase activity
GO:0017064 fatty acid amide hydrolase activity
Biological Process
GO:0006631 fatty acid metabolic process
GO:0006665 sphingolipid metabolic process
Cellular Component
GO:0005576 extracellular region
GO:0005764 lysosome

View graph for
Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:5u84, PDBe:5u84, PDBj:5u84
PDBsum5u84
PubMed29692406
UniProtA0A383ZFX3|ASAH1_BALAS Acid ceramidase (Gene Name=ASAH1)

[Back to BioLiP]