Structure of PDB 5u4h Chain B

Receptor sequence

>5u4hB (length=420) Species: 470 (Acinetobacter baumannii)

NAMDKFLITGGVKLEGEVRISGAKNAALPLLAAMILADSPITLTNVPNLK
DVNTLVKLIGGLGVTISYENDTVKADTSTLDNQFAPYELVKTMRASILVL
GPLLARYGNAKVSLPGGCAIGSRPVDQHLKALEALGAHIEVENGYVHATV
DGRLKGGEVVFDMVTVGGTENILMAAALADGVTTIRNAAREPEITDLAQM
LIKMGAKIEGLDTDTLVVTGVESLHGCEYAVVADRIETGSYLAAAAITGG
RVKTTHTDPSLLEAVLDKFEEMGAEVTRGDDWIELDMLGKRPKAVSFRTL
PHPEFPTDMQAQIMAVNAIGRGFATISETIFENRFMHVPELSRMGANIQV
EGHDAVVTGVEKLQAAPVMATDLRASFSLVLAALVAEGDTLIDRIYHIDR
GYEHVEEKLQGLGAKIKRVS

3D structure

• PDB: 5u4h 1.05 Angstrom Resolution Crystal Structure of UDP-N-acetylglucosamine 1-carboxyvinyltransferase from Acinetobacter baumannii in Covalently Bound Complex with (2R)-2-(phosphonooxy)propanoic Acid.
• Chain: B
• Resolution: 1.05 Å

Enzymatic activity

• Catalytic site (original residue number in PDB): K22 N23 D49 R92 C116 R121 D306 H335 L371 R372 R398
• Catalytic site (residue number reindexed from 1): K24 N25 D51 R94 C118 R123 D308 H337 L373 R374 R400
• Enzyme Commision number: 2.5.1.7: UDP-N-acetylglucosamine 1-carboxyvinyltransferase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	0V5	B	R92 C116 R398	R94 C118 R400

Gene Ontology

Molecular Function

• GO:0003824 catalytic activity
• GO:0008760 UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity
• GO:0016740 transferase activity
• GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups

Biological Process

• GO:0008360 regulation of cell shape
• GO:0009252 peptidoglycan biosynthetic process
• GO:0019277 UDP-N-acetylgalactosamine biosynthetic process
• GO:0051301 cell division
• GO:0071555 cell wall organization

Cellular Component

• GO:0005737 cytoplasm

External links

• PDB: RCSB:5u4h, PDBe:5u4h, PDBj:5u4h
• PDBsum: 5u4h
• UniProt: A0A0R0VXX6