Structure of PDB 5u3v Chain B

Receptor sequence
>5u3vB (length=268) Species: 9606 (Homo sapiens) [Search protein sequence]
PQVADLKAFSKHIYNAYLKNFNMTKKKARSILTGKAAPFVIHDIETLWQA
EKGLVWKQLVNGLPPYKEISVHVFYRCQCTTVETVRELTEFAKSIPSFSS
LFLNDQVTLLKYGVHEAIFAMLASIVNKDGLLVANGSGFVTREFLRSLRK
PFSDIIEPKFEFAVKFNALELDDSDLALFIAAIILCGDRPGLMNVPRVEA
IQDTILRALEFHLQANHPDAQYLFPKLLQKMADLRQLVTEHAQMMQRIKK
TETETSLHPLLQEIYKDM
3D structure
PDB5u3v Structural basis for specific ligation of the peroxisome proliferator-activated receptor delta.
ChainB
Resolution1.84 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 B7G B K283 E435 K111 E263
BS02 7TY B W228 C249 T252 T253 I290 V305 V312 I328 K331 H413 L433 Y437 W56 C77 T80 T81 I118 V133 V140 I156 K159 H241 L261 Y265
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004879 nuclear receptor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:5u3v, PDBe:5u3v, PDBj:5u3v
PDBsum5u3v
PubMed28320959
UniProtQ03181|PPARD_HUMAN Peroxisome proliferator-activated receptor delta (Gene Name=PPARD)

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