Structure of PDB 5u1c Chain B

Receptor sequence
>5u1cB (length=172) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence]
CSPGIWQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLA
GRWPVKTVHTDNGSNFTSTTVKAACWWAGIQSMNKELKKIIGQVRDQAEH
LKTAVQMAVFIHNFKAGERIVDIINFRVYYRDSRDPVWKGPAKLLWKGEG
AVVIQDNSDIKVVPRRKAKIIR
3D structure
PDB5u1c Cryo-EM structures and atomic model of the HIV-1 strand transfer complex intasome.
ChainB
Resolution3.9 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.7.-
2.7.7.49: RNA-directed DNA polymerase.
2.7.7.7: DNA-directed DNA polymerase.
3.1.-.-
3.1.13.2: exoribonuclease H.
3.1.26.13: retroviral ribonuclease H.
3.4.23.16: HIV-1 retropepsin.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 dna B R228 R263 R131 R166
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003677 DNA binding
GO:0004521 RNA endonuclease activity
GO:0008270 zinc ion binding
Biological Process
GO:0015074 DNA integration

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Molecular Function
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Biological Process
External links
PDB RCSB:5u1c, PDBe:5u1c, PDBj:5u1c
PDBsum5u1c
PubMed28059769
UniProtP12497|POL_HV1N5 Gag-Pol polyprotein (Gene Name=gag-pol)

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