Structure of PDB 5tzf Chain B

Receptor sequence
>5tzfB (length=76) Species: 953739 (Streptomyces venezuelae ATCC 10712) [Search protein sequence]
PKLVLDLERLAHVPQEKAGPLQRYAATIQSQRGAYNGKVLSIRQDDLRTL
AVIYDQSPSVLTEQLISWGVLDADAR
3D structure
PDB5tzf The Streptomyces master regulator BldD binds c-di-GMP sequentially to create a functional BldD2-(c-di-GMP)4 complex.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 C2E B I110 Q113 R114 R125 D128 I28 Q31 R32 R43 D46 PDBbind-CN: -logKd/Ki=5.80,Kd=1.6uM
BS02 C2E B R114 S123 R125 Q126 R32 S41 R43 Q44 PDBbind-CN: -logKd/Ki=5.80,Kd=1.6uM
Gene Ontology
Biological Process
GO:0045892 negative regulation of DNA-templated transcription

View graph for
Biological Process
External links
PDB RCSB:5tzf, PDBe:5tzf, PDBj:5tzf
PDBsum5tzf
PubMed28449057
UniProtF2RCL8

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