Structure of PDB 5txe Chain B

Receptor sequence
>5txeB (length=652) Species: 573065 (Asticcacaulis excentricus CB 48) [Search protein sequence]
APPVTPEVLVRLADIGTMSASETTPLLSLSPDGRYVAFQVRQADPVTNLN
VFRMVVKATDGATDAIDVDVGGEYLFWTIPSWGYARNAPSGANLTIQPRW
SPSGTHLAYLRQDQGRVRVWRASVKGEGASPVIEDAYDIEDVQWLDDNTL
IYSGRPGFVEAEAEIEREGRRGWVYDERFHPLTGARPRVLEPISIVYQVL
DLKTGTRRAATPTEVARLREKPDPLRAMVGRTTFSVSRTDPQNINAPTTL
VARRGEGEPVRCDEEACQNITRMWGDETANVLYFLRREGWASNEMALYRM
PADALKPVRIWHATGLLQGCERQAKRLICAQESALQPRRLVTLNLTSGQM
SPLYDPNPDLSRYRLPKVERLTLRNRNGIEVFSDLVLPPDYQLGTRLPLV
IVQYSSRGFLRGGTGDENPILPLATAGFAVLSFHSPRSEASYQRFTSPIA
QSKAEYSNWRNRWNILHTLEDLIDDLDRRGVIDPARVGLTGLADGATTVH
FGLINSHRFAAAVTSSCCTDSFTASVMNGPRISGALKAYGIETDQADDGP
FWAATSFVVNASRLDTPLLIQSADEEYLGALPGFTALQQARKPVELIIYP
NEHHVKWQPAHRLAVYNRTIDWFRFWLMDQSDPAPDKAAQYDRWRALRAL
RQ
3D structure
PDB5txe Structure of the Lasso Peptide Isopeptidase Identifies a Topology for Processing Threaded Substrates.
ChainB
Resolution2.2 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 3.4.-.-
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 peptide B S53 W111 I113 S115 W116 S124 A126 H214 L216 Y438 A527 N562 Y573 H638 S19 W77 I79 S81 W82 S90 A92 H180 L182 Y404 A493 N528 Y539 H604
Gene Ontology
Molecular Function
GO:0008236 serine-type peptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function

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Biological Process
External links
PDB RCSB:5txe, PDBe:5txe, PDBj:5txe
PDBsum5txe
PubMed27998080
UniProtE8RUP5|ATXE2_ASTEC Lasso peptide isopeptidase AtxE2 (Gene Name=atxE2)

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