Structure of PDB 5tn8 Chain B

Receptor sequence
>5tn8B (length=235) Species: 9606 (Homo sapiens) [Search protein sequence]
LSLTADQMVSALLDAEPPILYSEYDPTRPFSEASMMGLLTNLADRELVHM
INWAKRVPGFVDLTLHDQVHLLECAWLEILMIGLVWRSMEHPGKLLFAPN
LLLDRNQGKCVEGMVEIFDMLLATSSRFRMMNLQGEEFVCLKSIILLNSG
VYTFSLEEKDHIHRVLDKITDTLIHLMAKAGLTLQQQHQRLAQLLLILSH
IRHMSNKGMEHLYSMKCKNVVPLSDLLLEMLDAHR
3D structure
PDB5tn8 Systems Structural Biology Analysis of Ligand Effects on ER alpha Predicts Cellular Response to Environmental Estrogens and Anti-hormone Therapies.
ChainB
Resolution2.652 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B I358 K362 Q375 L539 E542 I51 K55 Q68 L226 E229
BS02 7G3 B E353 L387 M388 L391 M421 L525 E46 L80 M81 L84 M114 L212
External links
PDB RCSB:5tn8, PDBe:5tn8, PDBj:5tn8
PDBsum5tn8
PubMed28042045
UniProtP03372|ESR1_HUMAN Estrogen receptor (Gene Name=ESR1)

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